Notice
- Important: This guidance is under active development by NHS England and content may be added or updated on a regular basis.
- This Implementation Guide is currently in Draft and SHOULD NOT be used for development or active implementation without express direction from the NHS England Genomics Unit.
Composition
Composition-EULabGenomicReport-Example
Example of a structure report containing documents generated by the central broker for capturing snapshots of Test orders and results. This report aligns to HL7 EU Laboratory IG guidance.
| Composition |
| id : Composition-EULabGenomicReport-Example |
| meta |
| profile : http://hl7.eu/fhir/laboratory/StructureDefinition/Composition-eu-lab |
| extension |
| url : http://hl7.eu/fhir/StructureDefinition/composition-basedOn-order-or-requisition |
| value |
| reference : ServiceRequest/ServiceRequest-WGSTestOrderFormUpdated-TrioTesting-Example |
| extension |
| url : http://hl7.eu/fhir/StructureDefinition/information-recipient |
| value |
| reference : PractitionerRole/PractitionerRole-EugeneSmith-Example |
| extension |
| url : http://hl7.eu/fhir/laboratory/StructureDefinition/composition-diagnosticReportReference |
| value |
| reference : DiagnosticReport/DiagnosticReport-GenomicVariantAssessment-Example |
| status : final |
| type |
| coding |
| system : http://loinc.org |
| code : 51969-4 |
| display : Genetic analysis report |
| category |
| coding |
| system : http://loinc.org |
| code : 26436-6 |
| display : Laboratory studies (set) |
| category |
| coding |
| system : http://snomed.info/sct |
| code : 1236877003 |
| display : Genetic pathology |
| subject |
| reference : Patient/Patient-PheobeSmitham-Example |
| date : 2023-10-16T00:00:00-05:00 |
| author |
| identifier |
| system : https://fhir.nhs.uk/Id/ods-organization-code |
| value : R0A |
| title : Example Genomic Laboratory (Single) Report |
| section |
| title : Results |
| code |
| coding |
| system : http://loinc.org |
| code : 26436-6 |
| display : Laboratory studies (set) |
| entry |
| reference : Observation/Observation-GenomicTherapeuticImplication-Example |
| entry |
| reference : Observation/Observation-GenomicsVariantSLC52A2-Example |
{
},
{
}
},
{
}
},
{
}
}
],
]
},
{
]
},
{
]
}
],
},
],
{
]
},
{
},
{
}
]
}
]
}
</meta>
</valueReference>
</extension>
</valueReference>
</extension>
<extension url="http://hl7.eu/fhir/laboratory/StructureDefinition/composition-diagnosticReportReference">
</valueReference>
</extension>
</coding>
</type>
</coding>
</category>
</coding>
</category>
</subject>
</identifier>
</author>
</coding>
</code>
</entry>
</entry>
</section>
</Composition>
Composition-UGR-Example
Example of a Unified Genomic Record linking to patient demographics, test orders and results.
| Composition |
| id : Composition-UGR-Example |
| identifier |
| system : https://fhir.nhs.uk/Id/England-UnifiedGenomicRecord |
| value : 5acd7cf9-284e-4443-9763-2d1d8d524660 |
| status : final |
| type |
| coding |
| system : http://snomed.info/sct |
| code : 824321000000109 |
| display : Summary record |
| category |
| coding |
| system : http://snomed.info/sct |
| code : 321401000000106 |
| display : Genomics |
| subject |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449307539 |
| date : 2026-02-26T08:22:00Z |
| author |
| identifier |
| system : https://fhir.nhs.uk/Id/ods-organization-code |
| value : X26 |
| title : Unified Genomic Record Summary |
| confidentiality : R |
| custodian |
| identifier |
| system : https://fhir.nhs.uk/Id/ods-organization-code |
| value : X26 |
| section |
| title : Patient demographics |
| code |
| coding |
| system : https://fhir.hl7.org.uk/CodeSystem/UKCore-RecordStandardHeadings |
| code : patient-demographics |
| display : Patient demographics |
| text |
| status : generated |
| entry |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449307539 |
| section |
| title : Investigations and procedures requested |
| code |
| coding |
| system : https://fhir.hl7.org.uk/CodeSystem/UKCore-RecordStandardHeadings |
| code : investigations-and-procedures-requested |
| display : Investigations and procedures requested |
| text |
| status : generated |
| entry |
| reference : ServiceRequest/ServiceRequest-WGSTestOrderForm-TrioTestingProband-Example |
| section |
| title : Investigation results |
| code |
| coding |
| system : https://fhir.hl7.org.uk/CodeSystem/UKCore-RecordStandardHeadings |
| code : investigation-results |
| display : Investigation results |
| text |
| status : generated |
| entry |
| reference : DiagnosticReport/DiagnosticReport-GenomicVariantAssessment-Example |
{
},
]
},
{
]
}
],
},
],
},
{
{
}
]
},
},
]
},
{
{
}
]
},
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Test for R98.2, Likely inborn error of metabolism, 2026-01-13</div>"
},
]
},
{
{
}
]
},
"div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Positive for Brown-Vialetto-Van Laere syndrome</div>"
},
]
}
]
}
</identifier>
</coding>
</type>
</coding>
</category>
</identifier>
</subject>
</identifier>
</author>
</identifier>
</custodian>
</coding>
</code>
<div xmlns="http://www.w3.org/1999/xhtml">Pheobe Smitham, Female, DOB: 2013-09-27</div>
</text>
</identifier>
</entry>
</section>
</coding>
</code>
<div xmlns="http://www.w3.org/1999/xhtml">Test for R98.2, Likely inborn error of metabolism, 2026-01-13</div>
</text>
</entry>
</section>
</coding>
</code>
<div xmlns="http://www.w3.org/1999/xhtml">Positive for Brown-Vialetto-Van Laere syndrome</div>
</text>
</entry>
</section>
</Composition>